Compass Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company developing proprietary antibody-based therapeutics to treat multiple human diseases. Compass’ scientific focus is on the relationship between angiogenesis, the immune system and tumor growth. Our pipeline of novel product candidates is designed to target multiple critical biological pathways required for an effective anti-tumor response. These include modulation of the microvasculature via angiogenesis-targeted agents, induction of a potent immune response via activators on effector cells in the tumor microenvironment, and alleviation of immunosuppressive mechanisms used by tumors to evade immune surveillance. We plan to advance our product candidates through clinical development as both standalone therapies and in combination with proprietary pipeline antibodies based on supportive clinical and nonclinical data. We were founded in 2014 and are headquartered in Boston, Massachusetts. For more information, visit www.compasstherapeutics.com.

Our Discovery team is seeking a highly motivated and hands-on experienced Scientist, specific job level and title will be determined based on experience. The ideal candidate will have the desire to be part of a fast-paced and collaborative team. This position works in our lab and vivarium, and reports in-person onsite to our office in Brighton, MA.

Expectations

Ensure that Compass Discovery Research goals are on track to reach milestones within established timelines; support company goals through successful work in vivo and in vitro
Implement in vivo mouse models to test Compass molecules, being able to select right tumor models, design appropriate experiments to examine therapeutic concepts, perform experiments thoroughly, and interpret experimental results accurately
This role demands deep scientific expertise in order to make critical and timely decisions in close collaboration with the SVP of Discovery Research; includes a high level of transparency and scientific discussion
Work independently but also collaboratively as part of a team, to drive significant and time-sensitive projects to support early drug discovery
Deliver strong rigorous research that will provide scientific contribution to multiple research programs, critical department projects, inform research and company goals
Design and analyze experiments, interpret, and track results, and utilize findings for further assay development and optimization
Build and maintain strong relationships, and mentor team members on in vivo processes and procedures for further application in Discovery Research
Effectively adapt to changes and overall research restructure, and be open to suggestions and constructive criticism through the transition and thereafter
Thoroughly document and report experimental findings and record lab observation with the highest attention to detail in an ELN (electronic lab notebook)
Demonstrate a can-do attitude and risk-taking spirit; have the courage to explore new experiments and concepts

Qualifications

PhD with 3+ years of relevant experience, or 5+ years of experience with a Master’s degree; equivalent advanced degrees considered
Applicable experience preferred in the Biotech/Pharma industry, not required
Proven prior experience work independently in cancer biology or immunology required
Strong experience with the conduct of anti-tumor efficacy studies in mouse tumor models is a must; prior work with orthotopic tumor models is a plus
Demonstrated fundamental knowledge of basic immunological readouts, including FACS, Luminex, and ELISA
Prior experience with the application of ELISA to assess PK and ADA-response profiles is highly desired.
Comfortable with balancing multiple project objectives simultaneously and successfully, especially under tight timelines
Experience independently generating pharmacology reports & related documents for regulatory filings is highly desired
Competency with statistical data analysis using GraphPad Prism is desired
Proficiency with core Microsoft Office Suite is required
Self-motivated, meticulous, flexible and eager to take on new tasks
Excellent task management, written and verbal business communication skills

At Compass, we provide employees with an inclusive offering of benefits and a competitive compensation package. We offer our employees competitive salaries, discretionary bonuses, and meaningful equity participation. Our innovative benefits support the health and wellness of our employees; from medical, dental and vision benefits to health reimbursement arrangement, flexible spending accounts, sponsored gym membership, an employee assistance program, life insurance, and much more. We also provide 401(k) and Roth 401(k) programs with a 6% company match, and other resources for financial wellness. Additional benefits include commuter reimbursement, subsidized company parking, cell phone reimbursement, Summer Fridays, and substantial paid time off including a winter shut down week.

Our Mission at Compass is to develop next generation antibodies into transformative cancer therapies that improve patients’ lives. Our Compass Core Values guide us in achieving this. We are mission-focused and share a passion for science and creativity that help us innovate in all that we do. Our unique community promotes authenticity, diversity of thought, and collaborative teamwork.

We invest in the growth and development of our teams and individuals through programs such as company-wide trainings, cross-functional collaboration and job shadowing, tuition reimbursement, employee recognition awards, and a comprehensive performance management cycle. Also, our Compass Culture Committee empowers employee-organized events that celebrate wins, drive initiatives, support local philanthropy, and align with our mission and values.

Compass Therapeutics Inc.

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Discovery Scientist