Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI and San Diego, CA. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
The Lab Assistant will perform basic study support activities, as well as clerical and administrative duties to support In Vivo Pharmacology projects and research.
Responsibilities - Performs Routine Animal Handling and Restraint
- Ear tags animals and updates study logs.
- Regroup and sort animals based on study design
- Measures and records animal body weights
- Prepares / Assists with In Vivo Activities
- Prepares and aliquots buffers and solutions following standard operating procedures
- Labels tubes for blood and tissue collection
- Prepares dosing syringes
- Shaves animals in preparation for dosing/surgery
- Euthanizes animals as needed following standard operating procedures
- Centrifuges and aliquots blood samples
- Organizes study samples and delivers samples to appropriate location for analysis
- Communicates scheduling issues/changes to the In Vivo Pharmacology Project Manager
- Assist in the preparation and review of files for In Vivo studies
- Update study files and communicate study changes to the In Vivo Pharmacology
- Ensure In Vivo Pharmacology study files are accurate and complete
- Provide daily support to various areas within the In Vivo Pharmacology team, (i.e. aliquoting blood samples, organizing study materials)
- Update In Vivo study tracker files
- Record and circulate department meeting updates, as needed
- Performs other duties as needed
Requirements:
- Associate's Degree & some relevant experience (or High School Diploma & 3+ years of experience in a laboratory setting)
- Proficiency with Microsoft Suite programs (i.e. Excel, Word)
- Strong organizational skills
- Ability to prioritize tasks
- Strong attention to detail
- Ability to communicate to all levels of the organization
- Ability to adapt to changes in priority and/or studies
- Ability to work in fast paced environment
- Experience working in an animal laboratory
- Knowledge of In Vivo procedures and practices
Preferred:
- Background in animal husbandry, restraint and handling
- Must demonstrate a commitment to quality care of laboratory animals
California pay range
$50,000—$64,000 USD
Arrowhead provides competitive salaries and an excellent benefit package.
All applicants must have authorization to work in the US for a company.
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