About the Company and Role
Curve Biosciences™ (“Curve”) is pioneering the field of Chronic Epigenetics™ to bring precision to chronic disease care. Curve builds products targeting biological changes in tissues that occur in the development and progression of chronic diseases. Our Whole Body Tissue Atlas (WBTA) uniquely discovers such precise changes with data from over 250,000 tissues across more than 1,000 clinical studies. Curve’s initial focus is on chronic disease testing markets with a broader goal of unlocking our disease drivers for other clinical applications.
We are looking for a bioinformatician/data scientist to advance biomarker discovery capabilities and clinical test classifiers. Your expertise in biology and data science will propel our platform development and discovery efforts leading to the successful launch and adoption of novel blood testing products for chronic disease patients with unmet medical needs. This role is expected to initially provide hands-on individual contribution but can evolve to have functional leadership for our bioinformatics/data science strategy, teams and culture.
Job Responsibilities
Working directly with the Chief Scientific Officer and Bioinformatics/Data Science Lead, your responsibilities include but aren’t limited to:
- Building powerful biomarker discovery tools and selecting high performance biomarker sets leveraging Curve’s whole body tissue atlas (WBTA) of DNA methylation data from >250,000 samples from >100 tissue and disease states
- Further organizing and augmenting WBTA over time to build for new indications
- Identifying opportunities for leveraging machine learning in bioinformatics to gain insights and performance advantages from our data and build high-performance classifiers
- Working with the CEO to build foundation models and generative AI models from WBTA
- Developing bioinformatic pipelines and partnering with the laboratory teams to improve assay chemistry by providing computational analyses measuring assay performance
- Promoting a culture of scientific integrity, growth, transparency, collaboration, mutual respect, and fun, while valuing achieving progress to our goal of improving patient lives
Baseline Job Skills and Qualifications
- PhD in Bioinformatics, Biology, Computational Biology, Data Science, Computer Science or a related field; OR Masters in an above field with 2+ years of industry experience in bioinformatics/data science; OR Bachelors in an above field with 3+ years of industry experience in bioinformatics/data science
- Background in biology, machine learning, statistical analysis, and programming
- Experience with cloud environments and high-performance computing resources
- Understanding of next generation sequencing technology and cancer biology
- Ability/comfort in navigating change and uncertainty in a fast-paced environment
- Proven ability to collaborate and work cross-functionally to drive results quickly
- Demonstrated track record of getting things done and growing responsibility over time
- Strong interpersonal, organizational, analytical, communication and presentation skills
- Willing and able to travel as needed
Preferred Job Skills and Qualifications
- Deep understanding of next generation sequencing principles and pipelines
- Experience with foundation model development and generative AI
Employee Benefits
Curve Biosciences is dedicated to improving our patients’ lives and supporting our employees’ dreams. Some of our employee benefits include:
- Base cash salary range: $115,000 to $165,000 (does not include yearly cash bonus; title and base salary dependent on experience level)
- Early-stage equity with significant upside potential
- Flexible PTO
- Comprehensive health coverage, including medical, dental, and vision
- 401(k) plan with matching
- Training and support from successful leadership (past companies’ total value: ~$22B)
- Career opportunities for gaining depth in current role or breadth across other roles
- Career opportunities for honing individual contributor skills or gaining management skills
- Beautiful top-story labspace in San Mateo with state-of-the-art equipment and people
- Office space with daily lunches, snacks, and drinks
Curve Biosciences is an equal opportunity employer. We highly value diversity at our company and do not discriminate on the basis of race, religion, color, national origin, gender, age, sexual orientation, marital status, veteran status, or disability status.