The highly successful Laboratory for Inflammatory Skin Diseases at the Kimberly and Eric J. Waldman Department of Dermatology at Icahn School of Medicine at Mount Sinai, that is responsible for exciting discoveries leading to development off new treatments, is seeking a highly motivated Senior PhD-Level Scientist to join our expanding lab. The ideal candidate will work independently to design, execute, and interpret molecular and cellular assays and is comfortable in a fast-paced academic and entrepreneurial environment. This vital role will be responsible for genomic/proteomic aspects of the laboratory, ensuring timely delivery of analyses, performing and QC-ing analyses, and teaching and supervising assigned Research Associates.
This is a full-time on-site wet-lab role. As a valuable member of our team, you will contribute to the molecular studies underlying new treatments to treat Inflammatory Skin Disorders. You will be responsible for running scientific experiments and working in a cohesive cross-functional setting and support a team environment.
Responsibilities
- Execute and implement complex molecular biology protocols to characterize skin and blood samples.
- Execute assay and reagent troubleshooting, optimization, validation of experiments and appropriate documentation to support procedures and protocols, including data capture, forms, logbooks, and inventory batch records.
- On-boarding and development of new assays and Troubleshooting where required
- Keep detailed records of work and testing
- Supervise method and instrument qualification and validation.
- Summarize methods for publications and assist with publications for scientific journals.
- Effectively plan and ensure project deliverables and timelines are met.
- Train and mentor junior staff and research fellows to implement new technologies
Qualifications
- PhD in areas of Immunology OR Transcriptomics with 1-3 years of post PHD experience (Required)
- Experience in NGS, Single Cell and/or Spatial transcriptomics (Required)
- Experience with platforms of 10X Chromium, Vizgen-MERSCOPE or 10X Visium/Xenium or Nanostring GeoMx (Required)
- Experience with Flow Cytometry (Plus)
- Experience documented through notable authorship in peer reviewed publications (Required)
- Willingness to learn, adapt and support a cohesive team environment
- Excellent attention to detail and ability to follow protocols accurately
- Strong analytical and problem-solving skills
- Ability to work both independently and collaboratively in a team environment (Required)
- Effective verbal and written communication skills (Required) and ability to document and present research findings
- A minimum 2-year commitment required