Job Title: Scientist (In-Vitro Disease Modeling)
Work Location: Cambridge, MA
Contract Duration: 24 Months + Possible Extension/Conversion
Working Hours: Mon – Fri, 8AM – 5PM
NOTE: Position is in Cambridge, MA. This is a lab based onsite role. Candidates must be flexible and able to accommodate the change.
Qualifications
Education requirements:
- BS with 5+ years of experience/Masters with 3+ years of experience/PHD with 1+ year of experience in a wet lab setting.
- Candidates with a background in muscle biology will be given preference.
Required Experience And Skills
- Skilled in cell culturing and differentiation of stem cells into specific lineages.
- Experience with gene manipulation technologies such as CRISPR, siRNA, ASOs, lentivirus, and AAVs.
- Expertise in molecular biology techniques including RNA extraction, qPCR, ELISA/MSD, and ICC.
- Critical thinking with an ability to formulate experimental strategies.
- Effective in working independently and collaboratively within a team.
- Outstanding verbal and written communication skills.
Day To Day
- Muscle work
- Heavy wet lab-based position.
- Culture the cells.
- Work on Assay development.
- Role requires more precision to design experiments, culture cells and assay development.
- Team environment
- Discuss the experimental strategy with other scientists.
- Develop experimental plan (discuss, analyze, and present experimental plans)
- Present the data in a group meeting to other scientists.
- Use ELN
Responsibilities
Genome Sciences department in MRL is looking for a motivated scientist to lead the identification and validation of new genetic targets for various cardiometabolic diseases including Type 2 Diabetes (T2D), Obesity, Atherosclerosis, Retinal diseases, and vascular diseases. This individual will play a pivotal role as a member of the discovery team, contributing to the development of innovative models for screening drug targets.
Job Responsibilities
- Establish stem cell-based in-vitro disease platforms.
- Design assays using high content imaging techniques to facilitate screening of small molecules and genetic modifications using CRISPR.
- Perform lab experiments, interpret data, and effectively communicate findings.
- Collaborate with cross-functional teams in therapeutic and functional areas.
- Maintain electronic lab notebook and sample inventories.