About The Job
We are an innovative global healthcare company that helps the world stay ahead of infectious diseases by delivering more than 500 million vaccine doses a year. Across different countries, our talented teams are exploring new technologies to protect people and promote healthy communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.
Our Team: Sanofi Pasteur is seeking a creative and highly motivated molecular/synthetic biologist to join the vaccine research group in Cambridge, MA. The primary objective for this individual will be to develop innovative approaches to enable rapid prototyping of vaccine candidates against viral pathogens.
The successful candidate will design, perform, and execute complex laboratory experiments in molecular and synthetic biology. It is imperative that this candidate has an expert level, hands-on experience with sophisticated, high-throughput molecular cloning techniques and next-generation technologies in synthetic biology.
The successful candidate will also have working knowledge of high-throughput screening (HTS) methods for cloning, protein production, and primary screens for correctly folded protein antigens. A fundamental understanding of automation systems as well as data management/analysis/visualization and various other computational aspects which accompany HTS approaches is desired.
The successful candidate will be responsible for performing critical data analyses and for independently preparing and delivering impactful presentations to senior team members and to the global project team. This person will perform some aspects of project management.
Main responsibilities:
- Lead the in-house effort on high through-put plasmid preparation to various needs.
- Independently develop and optimize experimental assays to meet project objectives.
- Research, propose, and implement next-generation technologies to increase efficiency of high-throughput screening efforts in an Agile work environment.
- Work with internal Automation/Digital/Computational teams to implement data management best practices and ensure that data will be formatted for AI and ML applications.
- Serve as a laboratory lead to design and execute experiments with scientific staff that comply with study protocols and maintain scientific norms (contain appropriate positive and negative controls, replicates, standards, etc.) to appropriately achieve goals set forth in study plans.
- Demonstrate technical proficiency with the ability to problem solve in a broad array of experimental protocols.
- Provide guidance to junior personnel regarding protocol development, execution, and data validation.
- Help to lead, monitor, and maintain facility related aspects of the lab and lab equipment as needed
Project Contribution
- Present concise scientific presentations in-line with project objectives
- Interact with global project teams as a project liaison
- Support and in some cases lead internal site-specific projects.
- Assist with and/or prepare publications, proposals, reports, patents, and grant applications
- Critically evaluate relevant literature to provide experimental and strategic input to senior team members as needed.
- Actively take part in the training of technical staff
GRP and HSE
- Comply with the company safety policies and HSE to minimize risk to self, others and the environment, consistent with HSE policies, community and industry standards.
- Identify and help to improve best practices in HSE operations.
- Ensure documentation of laboratory experiments are entered in ELSE in a timely manner: analyze and summarize experimental outcomes, record experimental procedures and raw and analyzed data.
- Participate in generating/reviewing SOPs and other required documents
- Remain compliant with applicable trainings.
- About you
- Experience: Previous experience working in the industry (2-5 yrs), preferably in HTP on molecular/synthetic biology or equivalent discipline.
- Skills:
- Extensive hands-on expertise in hands-on experience in synthetic biology, molecular cloning, and protein expression in various upstream systems
- Extensive experience with automated or semi-automatic platforms in assay use
- Molecular Biology applications: PCR, cloning, RNA extraction, RT-PCR, Sequencing analysis
- Ability and willingness to train others on cross functional assays as well as develop new methodologies as needed
- Hands-on experience with scientific software for advanced data analytics and visualization is a plus: Genious, snapgene, Prism, Tableau, or Sequener
- Experience working in an agile, matrixed environment
- Leadership skills, entrepreneurial mindset, and experience managing scientists experimentation/workflow for a program
- Displays a high degree of integrity, decides and acts in the best interest of the Company
- Proficient interpersonal, communication, presentation, and negotiation skills
- Resourcefulness: ability to find tactical solutions to challenges
- Strongly results-oriented and data-driven, track record of delivery against challenging viral vaccine targets with aggressive timelines
- Performance-oriented with ability to deliver against extremely aggressive timelines
- Education: Advanced degree, PhD: +2 yrs; MSc: +5 yrs;
- Languages: English
Why Choose Us
- Bring the miracles of science to life alongside a supportive, future-focused team.
- Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
- Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
- Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
#GD-SP
Pursue
progress, discover
extraordinary
Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.
At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.
Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!