Seeking a contractor to execute existing laboratory automation workflows on our high-throughput antibody and protein production platforms. Specifically, to perform weekly expression runs for hundreds of antibodies to support early discovery efforts.
In this role you will build and then use a combination of protein expression, purification, and laboratory automation skills.
This role will require an eagerness to learn and an ability to work with different teams and different equipment to operate a robust high throughput protein production platform.
Your efforts will be a complement and core resource to existing capabilities and will serve to expand the team's ability to interrogate antibody/protein diversity in order to identify optimal leads. You will have the opportunity to apply your enthusiasm and technical skills as a member of Discovery Biologics - Boston to support and help drive multidisciplinary biotherapeutic discovery programs.
Responsibilities
- Operate and maintain existing liquid handling platforms including Lynx, Hamilton and Tecan to drive our small-scale automated protein production platforms.
- Troubleshoot automation methods and devices to maintain optimal high throughput protein production (yield, reproducibility, reliability, etc.).
- Generate frequent production summary reports.
- Follow and improve Standard Operating Procedures for expression and purification workflows.
Qualifications:
Contractor – High-Throughput Protein Production
Required Qualifications, experience and skills:
- A minimum of a B.S degree with 1-2 years of experience in a relevant field (e.g. protein sciences, chemical or bioengineering, biochemistry or similar) with additional training being desirable.
- Experience with cell culture, aseptic techniques, and protein/antibody production workflows and their inherent data management.
- Strong problem solving and communication skills.
- Ability to multitask, time management, and prioritize activities.
Preferred/Nice to have experience and skills:
- Experience with operating TECAN and/or other liquid handling platforms.
- Experience working with transient expression systems (HEK/CHO).
- Experience with programming languages such as Python.
Key skills/must haves:
- Cell culture experience
- Aseptic techniques
- Research tech experience
- Lab experience with in academia or industry