OCMS Bio is a new Enterprise Biotech Company providing proprietary tools and services to the monoclonal antibody industry. Our proprietary technology On-Cell mAb Screening (OCMS - pronounced as in "Occam's razor"), greatly speeds antibody discovery. OCMS fluorescent imaging methods transform mAb discovery from patient-derived antibodies, transgenic mouse models, and Artificial Intelligence (AI) antibody engineering.
Looking for individuals skilled in recombinant protein production in mammalian cells, hybridomas, cell culture. Candidates require at a minimum 2 years of relevant bench experience. Prior experience in industry is highly preferred. Looking primarily for a good fit with the company objectives. Salary and benefits will be commensurate with experience.
Experience requirements include but are not limited to:
- Design of oligos (or primers) for Ab mutant library
- Perform library construction using molecular biology technology (ex. Gibson Assembly) for viral transduction of mammalian cells.
- NGS sample preparation and analysis.
- Express antibodies in mammalian cells (ex. EXPI293 cells) for purification in various scales, including HT small scale.
- Designing and purification of various formats of antibodies and antigens with proper chromatography techniques ensuring high purity.
- Optimize and troubleshoot expression and purification strategies for proteins.
- Conjugate antibodies to other small molecules, such as biotin.
- Antibody binding and potency assays; On cell binding, ELISA, Neutralization, Western Blot, etc.
- Data analysis and presentation.
- Write SOPs.
- Design and implement workflows common for various projects.
- Serve as a subject matter expert in broader project-focused or group-focused team meetings.
- Train and supervise research technicians.