Chimerna Therapeutics is a New York City-based biotechnology company working on the next generation of circular RNA therapeutics. Chimerna is built on our Tornado circular RNA platform, a proprietary platform for the most efficient method of developing circular RNAs.

Chimerna is seeking a highly motivated and enthusiastic Research Associate with molecular and RNA biology experience, capable of working independently, to support platform development and pre-clinical program activities.

We aim to hire a collaborative, creative, and early- to mid-career scientist committed to building a high-performing and successful organization. As we are a start-up company, this position has tremendous room for professional growth and opportunities across multiple areas.

Key Responsibilities:

· Design and execute assays focused on circular RNA biology, including RNA isolation, purification, and characterization

· Perform various molecular biology activities including DNA cloning, bacterial propagation and induction, RNA and protein extraction, and immunoblotting

· Passage and maintain cell lines and perform tests to support the development and characterization of novel RNA therapeutic candidates

· Execute established assays and develop new assays to characterize therapeutic candidates

· Write standard operating procedures (SOPs) and maintain detailed, accurate, and timely records of experimental designs, results, data, and analysis

· Identify, evaluate, and troubleshoot problems related to experiments, including issues with instrumentation, reagents, and documentation

· Maintain detailed inventory records of cell lines, vectors, and reagents

· Support activities related to experiments such as media and buffer preparations

Minimum Requirements:

· Bachelor’s degree in Molecular Biology, Biochemistry, or related field

· Solid understanding of molecular biology techniques, including nucleic acid isolation, PCR, in vitro transcription, Western blotting

· Strong analytical and problem-solving skills with the ability to interpret experimental data

· Experience with aseptic cell culture techniques, including media preparation, cell line maintenance

· Effective communication skills to present scientific findings and collaborate with colleagues

· Ability to maintain a safe, clean, and organized work environment

Preferred Qualification:

· Master’s degree in Molecular Biology, Biochemistry, or related field

· Experience working with RNA, including RNA isolation, purification, and characterization techniques

· Proficiency in DNA cloning

· Hands-on experience with bacterial propagation and induction

· Advanced cell culture techniques such as single cell selection, DNA/RNA transfection, and lentiviral transduction

· Working knowledge of basic chromatography applications

· Experience with flow cytometry/FACS

Ability to commute/relocate

· New York, NY 10032: Reliably commute or planning to relocate before starting work (Required)

Education:

· Bachelor’s (required)

· Master’s (preferred)

Salary: $75,000 - $95,000 a year commensurate with experience

Job Type: Full-time

Benefits

· Health insurance

· Dental insurance

· Vision insurance

· Life insurance

· Flex spending account

· 4 weeks paid time off

· 401K with company match

· Commuter reimbursement

Chimerna Therapeutics

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