Chimerna Therapeutics is a New York City-based biotechnology company working on the next generation of circular RNA therapeutics. Chimerna is built on our Tornado circular RNA platform, a proprietary platform for the most efficient method of developing circular RNAs.
Chimerna is seeking a highly motivated and enthusiastic Research Associate with molecular and RNA biology experience, capable of working independently, to support platform development and pre-clinical program activities.
We aim to hire a collaborative, creative, and early- to mid-career scientist committed to building a high-performing and successful organization. As we are a start-up company, this position has tremendous room for professional growth and opportunities across multiple areas.
Key Responsibilities:
· Design and execute assays focused on circular RNA biology, including RNA isolation, purification, and characterization
· Perform various molecular biology activities including DNA cloning, bacterial propagation and induction, RNA and protein extraction, and immunoblotting
· Passage and maintain cell lines and perform tests to support the development and characterization of novel RNA therapeutic candidates
· Execute established assays and develop new assays to characterize therapeutic candidates
· Write standard operating procedures (SOPs) and maintain detailed, accurate, and timely records of experimental designs, results, data, and analysis
· Identify, evaluate, and troubleshoot problems related to experiments, including issues with instrumentation, reagents, and documentation
· Maintain detailed inventory records of cell lines, vectors, and reagents
· Support activities related to experiments such as media and buffer preparations
Minimum Requirements:
· Bachelor’s degree in Molecular Biology, Biochemistry, or related field
· Solid understanding of molecular biology techniques, including nucleic acid isolation, PCR, in vitro transcription, Western blotting
· Strong analytical and problem-solving skills with the ability to interpret experimental data
· Experience with aseptic cell culture techniques, including media preparation, cell line maintenance
· Effective communication skills to present scientific findings and collaborate with colleagues
· Ability to maintain a safe, clean, and organized work environment
Preferred Qualification:
· Master’s degree in Molecular Biology, Biochemistry, or related field
· Experience working with RNA, including RNA isolation, purification, and characterization techniques
· Proficiency in DNA cloning
· Hands-on experience with bacterial propagation and induction
· Advanced cell culture techniques such as single cell selection, DNA/RNA transfection, and lentiviral transduction
· Working knowledge of basic chromatography applications
· Experience with flow cytometry/FACS
Ability to commute/relocate
· New York, NY 10032: Reliably commute or planning to relocate before starting work (Required)
Education:
· Bachelor’s (required)
· Master’s (preferred)
Salary: $75,000 - $95,000 a year commensurate with experience
Job Type: Full-time
Benefits
· Health insurance
· Dental insurance
· Vision insurance
· Life insurance
· Flex spending account
· 4 weeks paid time off
· 401K with company match
· Commuter reimbursement